A comparative study of phytopreparations of Hepaklin and Silymarin in patients with metabolic syndrome and non-alcoholic fatty liver disease

Dorofeeva А.E. 1 , Rudenko N.N. 2 , Navka О.E. 3 , Silakov А.I.4

1 P.L. Shupika National Medical Academy of Postgraduate Education, Kiev, Ukraine

2 A.A. Bogomolets National Medical University, Kiev, Ukraine

3 Aviation Medical Center of the National Aviation University, Kiev, Ukraine.

4 KNP "Consultative and Diagnostic Center" of Svyatoshinsky district, Kiev, Ukraine

This century is characterized by an avalanche-like increase in the number of people with excessive body weight and obesity. For the past 35 years, the number of obese patients has doubled and reached 11% among men and 15% among women. The obesity has become a problem not only
in developed, but also in developing countries (Arroyo-Johnson C., Mincey K.D., 2016). In 2014, there were about 1.9 billion people with overweight and 650 million were obese. Our country is no exception. According to WHO, in 2016, 61.5% of adult Ukrainians had a body mass index (BMI) greater than 25. Currently, WHO characterizes obesity as the most important cause of developing chronic disease. It even outstripped the problem of malnutrition (WHO, 2016). This is due to the fact that overweight and obesity cause an increase of cardiovascular, endocrine and oncological pathologies (Yumuk V. et al., 2015).